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Switch medication from venlafaxine to duloxetine.[1] [2]
Stop venlafaxine - Day 1-14: gradually reduce dosage of venlafaxine to a maximum of 37,5 mg or 75 mg (slow release)/ day.
- Day 15: stop administration of venlafaxine
Start duloxetine- Day 15: start duloxetine 60 mg/day.[3]
- ↑ Switches are based on literature references on this page and expert opinions of the authors. The authors have used pharmacokinetic and receptor affinity properties to determine the switch schedules
- ↑ Stahl, S. M. (2013). Stahl's essential psychopharmacology: Neuroscientific basis and practical applications (4th ed.). Cambridge University Press.
- ↑ Wohlreich et al. Immediate switching of antidepressant therapy: results from a clinical trial of duloxetine. Ann Clin Psychiatry 2005 Oct-Dec;17(4):259-68
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