Combining-Lamotrigine-Ziprasidone
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Adding ziprasidone to lamotrigine.
General information- Lamotrigine is principally metabolised by UDP-glucuronosyltransferases.
- Ziprasidone is metabolized by CYP1A2 (minor) and CYP3A4.
- Ziprasidone is metabolized by CYP1A2 (minor) and CYP3A4.[4]
Start ziprasidone- Start ziprasidone according to the general dosing advice.
Cave- Central nervous system- and/or respiratory-depressant effects may be additively or synergistically increased in patients taking multiple drugs that cause these effects. [5]
- ↑ Farmacotherapeutisch Kompas; Toxicologie (dutch)
- ↑ Farmacotherapeutisch Kompas - lamotrigine (dutch)
- ↑ Drugs.com lamotrigine
- ↑ Bazire S; Psychotropic drug directory, 2007
- ↑ Interactions between ziprasidone and lamotrigine on drugs.com
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