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| to = imipramine
| stop =
| start =
* '''Day 115:''' simultaneously start administration of imipramine in a low dosage of 25 mg/day.* '''Day 8:''' stop administration of venlafaxine and continue administration of imipramine in a dosage of 50 mg/day.
| info =
* “Start low, go slow” for imipramine, and caution with this switch is necessary. * Venlafaxine is a weak inhibitor of CYP2D6, which metabolizes imipramine.}}