* '''Day 1:''' reduce dosage of duloxetine to a maximum of 30 mg/day.* '''Day 8:''' stop administration of duloxetine.

No wash-out period is needed.* '''Day 18:''' simultaneously start administration of dosulepine in a low dosage of 25-50 mg/day.* '''Day 815:''' stop administration of duloxetine and increase the dosage of dosulepine to 50-75 mg/day.

* Caution is necessary at the start of administration of dosulepine. {{theorSS}}}}