| stop =
* '''Day 0:''' gradually reduce dosage of duloxetine to a maximum of 60 mg/ day, when this dosage is > 60 mg/day.
* '''Day 1:''' reduce dosage of duloxetine to a maximum of 30 mg/day.* '''Day 8:''' stop administration of duloxetine.
| start =
No wash-out period is needed.* '''Day 18:''' simultaneously start administration of dosulepine in a low dosage of 25-50 mg/day.* '''Day 815:''' stop administration of duloxetine and increase the dosage of dosulepine to 50-75 mg/day.
| info =
* Duloxetine slows the metabolism of dosulepine by CYP2D6.
* Caution is necessary at the start of administration of dosulepine. {{theorSS}}}}