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| to = mianserine
| stop =
* '''Before day 01:''' gradually reduce dosage of sertraline to a maximum of 50 mg/ day, when this dosage is > 50 mg/day.
* '''Day 1:''' reduce dosage of sertraline to 25 mg/day.
| start =
* '''Day 1:''' simultaneously start administration of mianserine in a low dosage of 30 mg/day for one week.
* '''Day 8:''' stop administration of sertraline and continue administration of mianserine only. }}