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| stop =
* '''Day 1:''' reduce dosage of vortioxetine to 5 mg/day.
* '''Day 78:''' stop administration of vortioxetine.
| start =
* A wash-out period of 2 weeks is not necessary, but care is needed.{{Day22NoBloodlevelvortioxetine}}* '''Day 822:''' start administration of fluoxetine in a normal dosage of 20 mg/day.
| info =
* Occurrence of serotonin syndrome is theoretically possible, so caution is necessary.
* Fluoxetine is a strong inhibitor of CYP2D6, which metabolizes vortioxetine. }}