| to = bupropion

| stop =

| start =

* '''Day 4:''' simultaneously start administration of bupropion in a dosage of 150 mg/day and continue administration of imipramine according to the scheme above.

* Bupropion is a strong inhibitor of CYP2D6, which metabolizes imipramine.

* {{RiskSeizureBupropionTCA}}

}}