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| to = duloxetine
| stop =
{{stopImipramineTCAdecrease25p3d}}| start = * '''Day 4:''' simultaneously start administration of duloxetine in a normal dosage of 60 mg/day.* '''Day 8:''' stop administration of imipramine and continue administration of duloxetine.{{StartAntidepressant}}| info = * {{theorSS}}* Duloxetine is a inhibitor of CYP2D6, which metabolizes imipramine.Safe target dose duloxetine = 60 mg
}}