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| to = fluoxetine
| stop =
* '''Day 0Before day 1:''' gradually reduce dosage of mianserine to a maximum of 60 mg/ day.
* '''Day 1:''' reduce a dosage of 60 mg/day to 30 mg/day.
| start =
* '''Day 1:''' simultaneously start fluoxetine in a normal dosage of 20 mg/day.
* '''Day 8:''' stop administration of mianserine and only continue administration of fluoxetine only.
* If necessary, increase the dosage of fluoxetine.
| info =
* Fluoxetine Caution with this switch is a strong inhibitor necessary, because fluoxetine slows the metabolism of mianserine via CYP2D6, which metabolizes mianserine, so caution is necessary.}}