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| start =
* '''Day 1:''' simultaneously start fluoxetine in a normal dosage of 20 mg/day.
* '''Day 8:''' stop administration of mianserine and only continue administration of fluoxetine only.
* If necessary, increase the dosage of fluoxetine.
| info =
* Caution with this switch is necessary, because fluoxetine slows the metabolism of mianserine via CYP2D6.
}}