| to = amitriptyline
| stop =
* '''Day 1:''' reduce dosage of vortioxetine to 5 mg/day.* '''Day 8:''' stop administration of vortioxetine.{{Stopvortioxetine}}
| start =
No wash-out period is needed.* '''Day 8:''' start administration of amitriptyline in a dosage of 25 mg/day. * '''Day 15:''' continue administration of amitriptyline in a dosage of 50 mg/day. {{Day22NoBloodlevelvortioxetineTCAincrease25p3d}}
| info =
* {{theorSSTCAplasmalevelmonitoring}}
}}