* '''Day 8:''' stop administration of paroxetine
| start =
Caution is necessary.
* '''Day 8:''' start administration of amitriptyline in a low dosage of 25-50 mg/day.
* '''Day 15:''' if necessary increase dosage of amitriptyline to a dosage of 50-100 mg/day.
* Start low, go slow!
| info =
* Paroxetine slows the metabolism of amitriptyline via CYP2D6. }}