| to = duloxetine
| stop =
* Gradually reduce dosage of fluoxetine to a maximum of 20 mg/ day, when this dosage is > 20 mg/day. * When a dosage of 20 mg/day is reached, stop administration.{{stopfluox}}| start = No wash-out period is needed. * '''Day 1:''' start duloxetine the next day in low dosage of 30 mg/day for one week.* '''Day 28:''' increase dosage of duloxetine to normal, 60 mg/day.{{startnafluox}}
| info =
* Desmethylfluoxetine has a halflife of at least 1 week: it takes therefore 1 month for elemination.* Through CYP2D6 fluoxetine and duloxetine can mutually influence their metabolism.* {{theorSSlongt1/2fluvox}}* Safe target dose duloxetine = 60 mg
}}