* '''Before day 0:''' gradually reduce dosage of doxepin to a maximum of 100 mg/day.
* '''Day 1:''' reduce dosage of doxepin to 50 mg/day.
* '''Day 38:''' reduce dosage of doxepin to 25 mg/day.* '''Day 15:''' stop administration of doxepin.
| start =
Caution is necessary.* '''Day 18:''' simultaneously start administration of mirtazapine in a normal dosage of 30 mg/day.* '''Day 815:''' stop administration of doxepin and continue administration If necessary, increase dosage of mirtazapine.}}