* '''Day 1:''' reduce dosage of nortriptyline to 50 mg/day.
* '''Day 3:''' reduce dosage of nortriptyline to 25 mg/day.
* '''Day 8:''' stop administration of nortriptyline.
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* '''Day 1:''' simultaneously start administration of citalopram/escitalopram in a normal dosage of 20 mg/day, resp. 10 mg/day.* '''Day 8:''' stop administration of nortriptyline and continue administration of citalopram/escitalopram.
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* Citalopram/escitalopram are is a weak inhibitor of CYP2D6, which metabolizes nortriptyline.