Open main menu

Psychiatrienet β

Changes

Paroxetine-dosulepine

706 bytes added, 21:39, 3 May 2009
Created page with '{{Drugswitch | from = paroxetine | to = dosulepine | stop = * '''Day 0:''' gradually reduce dosage of paroxetine to a maximum of 20 mg/day when this dosage is > 20 mg/day. *...'
{{Drugswitch
| from = paroxetine
| to = dosulepine
| stop =
* '''Day 0:''' gradually reduce dosage of paroxetine to a maximum of 20 mg/day when this dosage is > 20 mg/day.
* '''Day 1:''' reduce dosage of paroxetine to a maximum of 10 mg/day.
* '''Day 8:''' reduce dosage of paroxetine to 5 mg/day.
| start =
Caution is necessary.
* '''Day 8:''' simultaneously start administration of dosulepine in a low dosage of 50 mg/day.
* '''Day 15:''' stop administration of paroxetine and only continue administration of dosulepine in a dosage of 50-75 mg/day.
* "Start low, go slow" is not required, but caution is necessary.
| info =
* Paroxetine possibly slows the metabolism of dosulepine via CYP2D6. }}
838
edits