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Created page with '{{Drugswitch | from = sertraline | to = nortriptyline | stop = * '''Day 0:''' gradually reduce dosage of sertraline to a maximum of 50 mg/ day when this dosage is > 50 mg/day...'
{{Drugswitch
| from = sertraline
| to = nortriptyline
| stop =
* '''Day 0:''' gradually reduce dosage of sertraline to a maximum of 50 mg/ day when this dosage is > 50 mg/day.
* '''Day 1:''' reduce dosage of sertraline to a maximum of 25 mg/day.
| start =
* '''Day 1:''' simultaneously start administration of nortriptyline in a low dosage of 25 mg/day.
* '''Day 8:''' stop administration of sertraline and continue administration of nortriptyline in a dosage of 50 mg/day
* “Start low, go slow” is not required, but caution is necessary.
| info = Sertraline dose-dependently slows the metabolism of nortriptyline via CYP2D6. }}
| from = sertraline
| to = nortriptyline
| stop =
* '''Day 0:''' gradually reduce dosage of sertraline to a maximum of 50 mg/ day when this dosage is > 50 mg/day.
* '''Day 1:''' reduce dosage of sertraline to a maximum of 25 mg/day.
| start =
* '''Day 1:''' simultaneously start administration of nortriptyline in a low dosage of 25 mg/day.
* '''Day 8:''' stop administration of sertraline and continue administration of nortriptyline in a dosage of 50 mg/day
* “Start low, go slow” is not required, but caution is necessary.
| info = Sertraline dose-dependently slows the metabolism of nortriptyline via CYP2D6. }}
