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Created page with '{{Drugswitch | from = bupropion | to = trazodone | stop = * Gradually reduce dosage of bupropion to a maximum of 150 mg/day. * When a dosage of 150 mg/day is reached, stop a...'
{{Drugswitch
| from = bupropion
| to = trazodone
| stop =
* Gradually reduce dosage of bupropion to a maximum of 150 mg/day.
* When a dosage of 150 mg/day is reached, stop administration.
| start =
* A wash-out period of one week is recommended.
* Start trazodone the next day in a normal dosage of 150 mg/day.
| info =
* Bupropion and its metabolites have long elimination times, so plasma concentrations will reduce gradually.
* Bupropion possibly slows the metabolismof trazodone by CYP2D6.}}
| from = bupropion
| to = trazodone
| stop =
* Gradually reduce dosage of bupropion to a maximum of 150 mg/day.
* When a dosage of 150 mg/day is reached, stop administration.
| start =
* A wash-out period of one week is recommended.
* Start trazodone the next day in a normal dosage of 150 mg/day.
| info =
* Bupropion and its metabolites have long elimination times, so plasma concentrations will reduce gradually.
* Bupropion possibly slows the metabolismof trazodone by CYP2D6.}}
