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| from = agomelatine
| to = hypericum
| stop = *'''Day 1:''' Stop agomelatine.{{StopAgomelatine}}
| start =
* ''' Day 2:''' Start administration of hypericum in a dosage of 300 mg three times a day (900 mg/day).
| info =
* No wash-out period is necessary.
* Hypericum induces the metabolism of agomelatine via CYP1A2.}}
