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Moclobemide-trazodone

139 bytes removed, 07:56, 21 October 2015
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| to = trazodone
| stop =
* '''Before day 1:''' gradually reduce dosage of moclobemide to a maximum of 300 mg/day, when this dosage is > 300 mg/day. * '''Day 1:''' reduce dosage of moclobemide to 150 mg/day.* '''Day 8:''' stop administration of moclobemide.{{stopMoclobemide}}
| start =
* '''Day 8-9:''' a wash-out period of two days is necessary. * '''Day 10:''' start administration of trazodone in a dosage of 100 mg/day.* '''Day 1716:''' if necessary, increase the dosage of trazodone to a maximum of 400 mg/day. 
| info =
* Because of short halve life of moclobemide after stopping, the next antidepressant can start next day.
* A wash-out period of is not necessary.
* Occurrence of the serotonin syndrome is theoretically possilble, so caution is necessary.
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