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Maprotiline-paroxetine

239 bytes removed, 13:53, 2 November 2015
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* '''Before day 1:''' gradually reduce dosage of maprotiline to a maximum of 75 mg/day.* '''Day 1:''' reduce dosage of maprotiline to 50 mg/day.* '''Day 7:''' reduce dosage of maprotiline to 25 mg/day.* '''Day 14:''' stop dosage of maprotiline.{{stopMaprotiline}}
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* '''Day 7:''' simultaneously start administration of paroxetine in a normal dosage of 20 mg/day.
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* Paroxetine is a strong inhibitor of CYP2D6, which metabolizes maprotiline.
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