| to = sertraline
| stop =
* '''Before day 1:''' gradually reduce dosage of trazodone to a maximum of 150 mg/day, when this dosage is > 150 mg/day. * '''Day 1:''' reduce dosage of trazodone to 75-100 mg/day.* '''Day 8:''' stop administration of trazodone.* '''Day 8-13:''' wash-out period{{stopTrazodone}}
| start =
* '''Day 9-14:''' wash-out period* '''Day 15:''' start administration of sertraline in a normal dosage of 50 mg/day.
| info =
* Sertraline dose-dependently inhibits CYP2D6, which metabolizes trazodone.
* The content of trazodone in the tablet, for example 100 mg or 150 mg, determines which exact doses are given. {{reviewtrazoTablet}} }}