{{stopVortioxetineTCAdecrease25p3d}}

{{washout8* '''Day 7 and after''': At approximately 50-14}}25% of the original vortioxetine dose start paroxetine at 50% of the target dose.* '''Day 1514:''' start administration of Increase paroxetine in a normal dosage to 100% of 10-20 mg/day.the target dose 

* {{theorSS}}Safe target dose paroxetine = 20 mg* Paroxetine paroxetine is a strong CYP2D6 inhibitor of CYP2D6, which metabolizes metabolize vortioxetine. }}