Difference between revisions of "Bupropion-vortioxetine"
From Psychiatrienet
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| to = vortioxetine | | to = vortioxetine | ||
| stop = | | stop = | ||
| − | + | {{StopBupropion}} | |
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| start = | | start = | ||
| − | * '''Day 1:''' | + | * ''' Day 1: ''' Start vortioxetine with a dosage of 5 mg/day. |
| + | * ''' Day 8: ''' increase dosage of vortioxetine to a dosage of 10 mg/day. | ||
| info = | | info = | ||
| − | * Bupropion | + | * Bupropion slows the metabolism of vortioxetine via CYP2D6 |
}} | }} | ||
Latest revision as of 11:48, 4 August 2023
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Switch medication from bupropion to vortioxetine.[1] [2]
Stop bupropion - Day 1: Stop bupropion.
- bupropion can be stopped abruptly for every dosage.[3]
Start vortioxetine- Day 1: Start vortioxetine with a dosage of 5 mg/day.
- Day 8: increase dosage of vortioxetine to a dosage of 10 mg/day.
More information- Bupropion slows the metabolism of vortioxetine via CYP2D6
- ↑ Switches are based on literature references on this page and expert opinions of the authors. The authors have used pharmacokinetic and receptor affinity properties to determine the switch schedules
- ↑ Stahl, S. M. (2013). Stahl's essential psychopharmacology: Neuroscientific basis and practical applications (4th ed.). Cambridge University Press.
- ↑ Multidisciplinair document Afbouwen Overige Antidepressiva 2023
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