Difference between revisions of "Doxepine-tranylcypromine"

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(Created page with '{{Drugswitch | from = doxepin | to = tranylcypromine | stop = * '''Day 0:''' gradually reduce dosage of doxepin to a maximum of 100 mg/ day, when this dosage is > 100 mg/day....')
 
 
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| to = tranylcypromine  
 
| to = tranylcypromine  
 
| stop =  
 
| stop =  
* '''Day 0:''' gradually reduce dosage of doxepin to a maximum of 100 mg/ day, when this dosage is > 100 mg/day.
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{{generaldecrease25p3d}}
* '''Day 1-3:''' reduce dosage of doxepin to 50 mg/day.
 
* '''Day 4-7:''' reduce dosage of doxepin to 25 mg/day.
 
* '''Day 8:''' stop administration of doxepin.
 
 
| start =  
 
| start =  
* '''Day 8-14:''' a wash-out period of one week is necessary.
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{{starttranyl}}
* '''Day 15:''' start administration of tranylcypromine in a normal dosage of 20 mg/day.}}
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| info=
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{{nowashout}}<ref name="informatorium">{{KNMP}}</ref>
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}}

Latest revision as of 12:24, 8 March 2024

Doxepin
Type antidepressant
Group TCA
links
ATC-code N06AA12
Medscape Doxepin
PubChem 3158
PubMed Doxepin
Drugs.com doxepin
Kompas (Dutch) Doxepin
Wikipedia Doxepin
Tranylcypromine
Type Antidepressant
Group MAO-I
links
Medscape Tranylcypromine
PubChem 5530
PubMed Tranylcypromine
Kompas (Dutch) Tranylcypromine
Wikipedia Tranylcypromine

Switch medication from doxepin to tranylcypromine.[2] [3]

Nietinrijdenbord.png Stop doxepin
  • Decrease with about 25% of original dose every 3 days
Eenrichtingbord.png Start tranylcypromine
  • Start tranylcypromine in a low dosage of 20 mg/day for one week.
  • After this week the dosage of tranylcypromine can be increased.
Infobord.png More information
  • No wash-out period is necessary[1]
  1. 1.0 1.1 1.2 1.3 1.4 1.5 KNMP; Informatorium Medicamentorum 2023; Monografie "doxepine" (Dutch) Cite error: Invalid <ref> tag; name "informatorium" defined multiple times with different content
  2. Switches are based on literature references on this page and expert opinions of the authors. The authors have used pharmacokinetic and receptor affinity properties to determine the switch schedules
  3. Stahl, S. M. (2013). Stahl's essential psychopharmacology: Neuroscientific basis and practical applications (4th ed.). Cambridge University Press.
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