| to = sertraline
| stop =
* Gradually reduce dosage of bupropion to a maximum of 150 mg/ day. * When a dosage of 150 mg/day is reached, stop administration.{{StopBupropion1}}| start = * No wash-out period is needed. * Start sertraline the next day in normal dosage of 50 mg/day.{{StartAntidepressant}}| info = * Bupropion and its metabolites have long elimination times, so plasma concentrations will reduce gradually.{{review}}Safe target dose sertraline = 100 mg
}}