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| stop =
{{stopBupropion}}
| start = {{Inc25p3d2StartAntidepressant}}* Start trazodone in a dosage of 100-150 mg/day. | info = * No wash-out period is needed.* Bupropion and its metabolites have long elimination times, so plasma concentrations will reduce gradually. Safe target dose trazodone = 150 mg
* Bupropion and its metabolites slow the metabolism of trazodone by CYP2D6.
}}