Open main menu

Psychiatrienet β

Changes

Fluoxetine-maprotiline

102 bytes removed, 20 February
no edit summary
| to = maprotiline
| stop =
* Gradually reduce dosage of fluoxetine to a maximum of 20 mg/ day, when this dosage is > 20 mg/day. * When a dosage of 20 mg/day is reached, stop administration.{{stopFluoxetine1}}
| start =
Caution is necessary for at least four weeks.* '''Day 15:''' start administration of maprotiline in a low dosage of 25 mg/day.* '''Day 815:''' increase dosage of maprotiline to 50 mg/day.* '''Day 1520 and after:''' gradually increase dosage of maprotiline to 75 mg/dayif necessary.
| info =
* {{TCAplasmalevelmonitoring}}* Fluoxetine slows and norfluoxetine slow the metabolism of maprotiline via CYP2D6. {{longt1/2fluvox}}
* Start low, go slow for maprotiline.}}