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* No wash'''Day 6 and after''': At approximately 50-out period is needed25% of the original venlafaxine dose start fluoxetine at 100% of the target dose. * Start fluoxetine the next day in a normal ''' After 3 weeks:''' If necessary, gradually increase dosage of 20 mg/dayfluoxetine.|info = {{review}}* Safe target dose fluoxetine = 20 mg* Fluoxetine and norfluoxetine are inhibitors of CYP2D6 (strong), which metabolizes venlafaxine. It prolongs the halftime of venlafaxine which decreases the chances of withdrawal
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