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Fluoxetine-clomipramine

46 bytes added, 14 April
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| stop = {{stopfluox}}
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Caution is necessary for at least four weeks.
* '''Day 5:''' start administration of clomipramine in a low dosage of 37.5 mg/day.
* '''Day 15:''' increase dosage of clomipramine to 75 mg/day.
* {{TCAplasmalevelmonitoring}}
* Tapering fluoxetine to 20mg before stopping is not necessary, because of strong serotonergic activity of target drug.
{{longt1/2fluvox}}
* Fluoxetine and norfluoxetine slow the metabolism of clomipramine via CYP2D6.
{{longt1/2fluvox}}
* Start low, go slow for clomipramine.
}}

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