Difference between revisions of "Sertraline-venlafaxine"
From Psychiatrienet
(Created page with '{{Drugswitch | from = sertraline | to = venlafaxine | stop = * Gradually reduce dosage of sertraline to a maximum of 50 mg/ day, when this dosage is > 50 mg/day. * When a do...') |
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| to = venlafaxine | | to = venlafaxine | ||
| stop = | | stop = | ||
| − | * | + | * '''Before day 0:''' gradually reduce dosage of sertraline to a maximum of 50 mg/ day, when this dosage is > 50 mg/day. |
| − | * | + | * '''Day 1:''' reduce dosage of sertraline to 25 mg/day. |
| + | * '''Day 8:''' stop administration of sertraline. | ||
| start = | | start = | ||
* No wash-out period is needed. | * No wash-out period is needed. | ||
| − | * | + | * '''Day 9:''' start venlafaxine the next day in normal dosage of 75 mg/day.}} |
Revision as of 15:24, 7 May 2009
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Switch medication from sertraline to venlafaxine.[1] [2]
Stop sertraline - Before day 0: gradually reduce dosage of sertraline to a maximum of 50 mg/ day, when this dosage is > 50 mg/day.
- Day 1: reduce dosage of sertraline to 25 mg/day.
- Day 8: stop administration of sertraline.
Start venlafaxine- No wash-out period is needed.
- Day 9: start venlafaxine the next day in normal dosage of 75 mg/day.
- ↑ Switches are based on literature references on this page and expert opinions of the authors. The authors have used pharmacokinetic and receptor affinity properties to determine the switch schedules
- ↑ Stahl, S. M. (2013). Stahl's essential psychopharmacology: Neuroscientific basis and practical applications (4th ed.). Cambridge University Press.
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