Difference between revisions of "Mianserine-venlafaxine"
From Psychiatrienet
(Created page with '{{Drugswitch | from = mianserine | to = venlafaxine | stop = * '''Day 0:''' gradually reduce dosage of mianserine to a maximum of 60 mg/ day. * '''Day 1:''' reduce a dosage o...') |
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* '''Day 1:''' reduce a dosage of 60 mg/day to 30 mg/day. | * '''Day 1:''' reduce a dosage of 60 mg/day to 30 mg/day. | ||
| start = | | start = | ||
| − | * '''Day 1:''' simultaneously start venlafaxine in a normal dosage of 75 mg/day. | + | * '''Day 1:''' simultaneously start venlafaxine in a normal dosage of 75 mg/day (slow relase). |
* '''Day 8:''' stop administration of mianserine and only continue administration of venlafaxine. | * '''Day 8:''' stop administration of mianserine and only continue administration of venlafaxine. | ||
| − | * If necessary, increase the dosage of venlafaxine. }} | + | * If necessary, increase the dosage of venlafaxine. |
| + | | info = | ||
| + | * Occurrence of serotonin syndrome is (not very likely) possible, so caution is necessary.}} | ||
Revision as of 15:44, 10 July 2009
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Switch medication from mianserine to venlafaxine.[1] [2]
Stop mianserine - Day 0: gradually reduce dosage of mianserine to a maximum of 60 mg/ day.
- Day 1: reduce a dosage of 60 mg/day to 30 mg/day.
Start venlafaxine- Day 1: simultaneously start venlafaxine in a normal dosage of 75 mg/day (slow relase).
- Day 8: stop administration of mianserine and only continue administration of venlafaxine.
- If necessary, increase the dosage of venlafaxine.
More information- Occurrence of serotonin syndrome is (not very likely) possible, so caution is necessary.
- ↑ Switches are based on literature references on this page and expert opinions of the authors. The authors have used pharmacokinetic and receptor affinity properties to determine the switch schedules
- ↑ Stahl, S. M. (2013). Stahl's essential psychopharmacology: Neuroscientific basis and practical applications (4th ed.). Cambridge University Press.
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