Difference between revisions of "Sulpiride-Sertindole"

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Revision as of 12:06, 14 August 2009

Sulpiride
Type Antipsychotic
Group Atypical AP
links
PubChem 5355
PubMed Sulpiride
Kompas (Dutch) Sulpiride
Wikipedia Sulpiride
Sertindole
Type Antipsychotic
Group Atypical AP
links
PubChem 60149
PubMed Sertindole
Kompas (Dutch) Sertindole
Wikipedia Sertindole

Switch medication from Sulpiride to Sertindole.[1] [2]

Nietinrijdenbord.png Stop Sulpiride
  • Day 1-4: approx. 75% of initial dose
  • Day 5-8: approx. 50% of initial dose
  • Day 9-12: approx. 25% of initial dose
  • Day 13: stop
Eenrichtingbord.png Start Sertindole
  • Day 1-4: approx. 50% of target dose
  • Day 5-8: approx. 75% of target dose
  • Day 9: target dose
Letopbord.png Cave
  • During this switch ECG monitoring is required because of possible QT-interval prolongation[3][4]


  1. Switches are based on literature references on this page and expert opinions of the authors. The authors have used pharmacokinetic and receptor affinity properties to determine the switch schedules
  2. Stahl, S. M. (2013). Stahl's essential psychopharmacology: Neuroscientific basis and practical applications (4th ed.). Cambridge University Press.
  3. SPC Sertindole (Dutch)
  4. SPC Sertindole
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