Difference between revisions of "Amisulpride-Aripiprazole"
From Psychiatrienet
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| − | | start = {{Start}}<ref>http://www.emea.europa.eu/humandocs/Humans/EPAR/abilify/abilify</ref> | + | | start = {{Start}} <ref>http://www.emea.europa.eu/humandocs/Humans/EPAR/abilify/abilify</ref> |
| − | | info = {{caveQT}}<ref>http://www.ncbi.nlm.nih.gov/pubmed/16096514?ordinalpos=6&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum</ref> | + | | info = {{caveQT}} <ref>http://www.ncbi.nlm.nih.gov/pubmed/16096514?ordinalpos=6&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum</ref> |
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Revision as of 09:51, 17 August 2009
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Switch medication from Amisulpride to Aripiprazole.[1] [2]
Stop Amisulpride - Week 1-3: approx. 75% of initial dose
- Week 4-6: approx. 50% of initial dose
- Week 7-9: approx. 25% of initial dose
- Week 10: stop
Start Aripiprazole- Day 1: Start drug at target dose [3]
More information- During this switch you could monitor ECG, especially in patients prone to QT-conduction problems.
- There is a possibility of QT interval prolongation.[4]
— Amisulpride — Aripiprazole
- ↑ Switches are based on literature references on this page and expert opinions of the authors. The authors have used pharmacokinetic and receptor affinity properties to determine the switch schedules
- ↑ Stahl, S. M. (2013). Stahl's essential psychopharmacology: Neuroscientific basis and practical applications (4th ed.). Cambridge University Press.
- ↑ http://www.emea.europa.eu/humandocs/Humans/EPAR/abilify/abilify
- ↑ Stöllberger C, Huber JO, Finsterer J, Antipsychotic drugs and QT prolongation. Int Clin Psychopharmacol. 2005 Sep;20(5):243-51.
- ↑ http://www.ncbi.nlm.nih.gov/pubmed/16096514?ordinalpos=6&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum
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