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| to = mianserine
| stop =
* '''Day 0Before day 1:''' gradually reduce dosage of duloxetine to a maximum of 60 mg/ day.
* '''Day 1:''' reduce a dosage of 60 mg/day to 30 mg/day.
* '''Day 8:''' stop administration of duloxetine.
| start =
* '''Day 18:''' simultaneously start mianserine in a normal low dosage of 30-40 mg/day.* '''Day 815:''' stop administration of duloxetine and continue with increase mianserine only. }}
