Difference between revisions of "Fluoxetine-nortriptyline"
From Psychiatrienet
(Created page with '{{Drugswitch | from = fluoxetine | to = nortriptyline | stop = * Gradually reduce dosage of fluoxetine to a maximum of 20 mg/ day, when this dosage is > 20 mg/day. * When a d...') |
(No difference)
|
Revision as of 19:33, 3 May 2009
| ||||||||||||||||||||||
| ||||||||||||||||||||||
Switch medication from fluoxetine to nortriptyline.[1] [2]
Stop fluoxetine - Gradually reduce dosage of fluoxetine to a maximum of 20 mg/ day, when this dosage is > 20 mg/day.
- When a dosage of 20 mg/day is reached, stop administration.
Start nortriptylineCaution is necessary for at least four weeks.
- Day 1: start administration of nortriptyline in a low dosage of 20 mg/day.
- Day 8: increase dosage of nortriptyline to 30 mg/day.
- Day 15: increase dosage of nortriptyline to 50 mg/day.
More information- Fluoxetine slows the metabolism of nortriptyline via CYP2D6.
- Start low, go slow for nortriptyline.
- ↑ Switches are based on literature references on this page and expert opinions of the authors. The authors have used pharmacokinetic and receptor affinity properties to determine the switch schedules
- ↑ Stahl, S. M. (2013). Stahl's essential psychopharmacology: Neuroscientific basis and practical applications (4th ed.). Cambridge University Press.
The editors of psychiatrienet.nl take the greatest care to provide up-to-date and accurate information on this site. Nevertheless, mistakes and omissions cannot be entirely excluded. No rights devolve from the information provided. The editors and other providers of information to this site accept no responsibility for the content of this site or for the information provided therein; neither do they accept responsibility for possible damages which may derive from the use of the information on this site or from the linked sites. The editorial board accepts no responsibility for the content of the (linked) sites, for access to them, or for the products and services on these sites, nor for the occurrence of errors, viruses, and/or disruptions in service.
