Difference between revisions of "Valproic acid"
From Psychiatrienet
| (4 intermediate revisions by the same user not shown) | |||
| Line 1: | Line 1: | ||
{{Drug | {{Drug | ||
| − | | name = | + | | name = Valproic acid |
| group = anticonvulsant | | group = anticonvulsant | ||
| − | + | | type = moodstabilizer | |
| − | | type = | ||
| wikipedia = valproic_acid | | wikipedia = valproic_acid | ||
| medscape = 8885 | | medscape = 8885 | ||
| Line 9: | Line 8: | ||
| pubchem = 3121 | | pubchem = 3121 | ||
| drugscom = valproic-acid-and-derivatives-divalproex-sodium-sodium-valproate | | drugscom = valproic-acid-and-derivatives-divalproex-sodium-sodium-valproate | ||
| + | | drugscomid = valproic-acid | ||
| ftk = valproinezuur | | ftk = valproinezuur | ||
| ATC = N03AG01 | | ATC = N03AG01 | ||
| − | | metabolization = Valproic acid is principally metabolized by CYP2C9, CYP2C19, CYP2A6 and UDP-glucuronosyltransferases. Valproic acid is an inhibitor of the enzymes CYP2C9, epoxide-hydroxylase and UDP-glucuronosyltransferases.<ref name="ftk">{{FTK|valproinezuur}}</ref> | + | | metabolization = * Valproic acid is principally metabolized by CYP2C9, CYP2C19, CYP2A6 and UDP-glucuronosyltransferases. Valproic acid is an inhibitor of the enzymes CYP2C9, epoxide-hydroxylase and UDP-glucuronosyltransferases. |
| − | < | + | | metabolization_ref = <ref name="ftk">{{FTK|valproinezuur}}</ref> |
| − | | isswitch = 1 | + | | administration = O,R |
| − | </includeonly> | + | | ctox = 150000 |
| + | | ctox_ref = <ref name="ftktox">{{ftktox}}</ref> | ||
| + | | cth = 50000-100000 | ||
| + | | halflife = 10-15 | ||
| + | | halflife_ref = <ref name="ftk">{{FTK|valproinezuur}}</ref> | ||
| + | | bioavailability = 100 | ||
| + | | bioavailability_ref = <ref name="informatorium">{{KNMP|valproaat}}</ref> | ||
| + | | <includeonly> isswitch = 1</includeonly> | ||
}} | }} | ||
Latest revision as of 00:19, 27 April 2010
| Valproic acid | |||||||||||||
| Type | moodstabilizer | ||||||||||||
| Group | anticonvulsant | ||||||||||||
| links | |||||||||||||
| ATC-code | N03AG01 | ||||||||||||
| PubChem | 3121 | ||||||||||||
| PubMed | acid%22 Valproic acid | ||||||||||||
| Drugs.com | valproic-acid | ||||||||||||
| Kompas (Dutch) | Valproic acid | ||||||||||||
| Wikipedia | Valproic acid | ||||||||||||
| |||||||||||||
"-100000" can not be assigned to a declared number type with value 50000.
"-15" can not be assigned to a declared number type with value 10.
Valproic acid is a moodstabilizer in the group anticonvulsant.
- Metabolization
- Valproic acid is principally metabolized by CYP2C9, CYP2C19, CYP2A6 and UDP-glucuronosyltransferases. Valproic acid is an inhibitor of the enzymes CYP2C9, epoxide-hydroxylase and UDP-glucuronosyltransferases.[2]
- ↑ Farmacotherapeutisch Kompas; Toxicologie (dutch)
- ↑ 2.0 2.1 Farmacotherapeutisch Kompas - valproinezuur (dutch)
- ↑ KNMP; Informatorium Medicamentorum 2023; Monografie "valproaat" (Dutch)
