Difference between revisions of "Olanzapine"

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{{Drug
 
{{Drug
 
| name = Olanzapine
 
| name = Olanzapine
| group = Atypical AP
+
| group = atypical AP
 +
| type = antipsychotic
 +
| otheruse = moodstabilizer
 
| pubchem = 4585
 
| pubchem = 4585
 
| medscape = 1644
 
| medscape = 1644
 
| emea = zyprexa
 
| emea = zyprexa
 
| ATC = N05AH03
 
| ATC = N05AH03
 +
| CAS = 132539-06-1
 +
| ChemSpiderID = 10442212
 +
| drugbank = APRD00138
 +
| drugscom = olanzapine
 
| ftk = olanzapine
 
| ftk = olanzapine
| type = Antipsychotic
 
| otheruse = Moodstabilizer
 
 
| metabolization = * Olanzapine is principally metabolized by CYP1A2 and CYP2D6.
 
| metabolization = * Olanzapine is principally metabolized by CYP1A2 and CYP2D6.
 
| start =  
 
| start =  
 
| stop =  
 
| stop =  
 +
| equivalent = 0.4
 +
| equivalent_ref = <ref>Woods SW Chlorpromazine equivalent doses for the newer atypical antipsychotics; ''J Clin Psychiatry'' 2003;'''64''':663-667</ref>
 +
| comparison = haloperidol
 +
<!--
 +
| avail = unknown
 +
-->
 +
| halflife = 32-52
 +
| halflife_ref = <ref name="informatorium">{{KNMP|olanzapine}}</ref>
 +
| ct = 11
 +
| ct_ref = <ref name="informatorium" />
 +
| administration = oral
 +
| dose = 2.5-20
 +
| dose_ref = <ref name="informatorium" />
 +
| DDD = 30
 +
| DDD_ref = <ref name="informatorium" />
 +
| ctox = 100
 +
| ctox_ref = {{FTK-TOX}}
 
| <includeonly>| isswitch = 1 </includeonly>
 
| <includeonly>| isswitch = 1 </includeonly>
 
}}
 
}}

Latest revision as of 00:20, 27 April 2010

Olanzapine
Type antipsychotic
Group atypical AP
Other use moodstabilizer
links
ATC-code N05AH03
Medscape Olanzapine
EMEA zyprexa
PubChem 4585
PubMed Olanzapine
Drugs.com olanzapine
Kompas (Dutch) Olanzapine
Wikipedia Olanzapine

"-52" can not be assigned to a declared number type with value 32.






Olanzapine is a antipsychotic in the group atypical AP. Olanzapine is also used as moodstabilizer.


Metabolization
  • Olanzapine is principally metabolized by CYP1A2 and CYP2D6.


  1. 1.0 1.1 1.2 1.3 KNMP; Informatorium Medicamentorum 2023; Monografie "olanzapine" (Dutch)
  2. Farmacotherapeutisch Kompas; Toxicologie (dutch)
  3. Woods SW Chlorpromazine equivalent doses for the newer atypical antipsychotics; J Clin Psychiatry 2003;64:663-667