Difference between revisions of "Stop-hypericum"

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{{Drugswitch
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* '''Day 1-14:'''Gradually decrease the dosage of hypericum.
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* '''Day 15:''' stop administration of hypericum.
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* 60 mg/day:
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:*'''Day 1-35:''' gradually reduce dosage of hypericum
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:* '''Day 36:''' stop administration of tranylcypromine.
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}}

Revision as of 10:16, 27 May 2010

Hypericum
Type Antidepressant
Group other
links
EMEA 10130408en
PubMed Hypericum
Kompas (Dutch) hypericum extract
Wikipedia St John's wort


Nietinrijdenbord.png Stop hypericum
  • In general after long-term maintenance treatment, the best is to reduce the dose by about 25% every 4-6 weeks. An apt pharmaceutical dose (tablet, capsule, mixture) is not always available. In these cases one should be creative with dosing.[1][2]
  • Another, more risky, possibility is being at a certain dose to use the following scheme:
  • 60 mg/day:
  • Day 1-35: gradually reduce dosage of hypericum
  • Day 36: stop administration of tranylcypromine.



  1. The UK Drug and Therapeutics Bulletin; 1999;37:49-52
  2. Editor: please note that not all dosages are available in pharmacy. So now and then you should be creative.
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