Difference between revisions of "Moclobemide-fluoxetine"

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Revision as of 11:56, 4 May 2009

Moclobemide
Type Antidepressant
Group MAO-I
links
Medscape Moclobemide
PubChem 4235
PubMed Moclobemide
Kompas (Dutch) Moclobemide
Wikipedia Moclobemide
Fluoxetine
Type Antidepressant
Group SSRI
links
Medscape Fluoxetine
PubChem 3386
PubMed Fluoxetine
Kompas (Dutch) Fluoxetine
Wikipedia Fluoxetine

Switch medication from moclobemide to fluoxetine.[1] [2]

Nietinrijdenbord.png Stop moclobemide
  • Gradually reduce dosage of moclobemide to a maximum of 300 mg/ day.
  • When a dosage of 300 mg/day is reached, stop administration.
Eenrichtingbord.png Start fluoxetine
  • Day 1-2: a wash-out period of two days is necessary.
  • Day 3: start fluoxetine after this period in a normal dosage of 20 mg/day.


  1. Switches are based on literature references on this page and expert opinions of the authors. The authors have used pharmacokinetic and receptor affinity properties to determine the switch schedules
  2. Stahl, S. M. (2013). Stahl's essential psychopharmacology: Neuroscientific basis and practical applications (4th ed.). Cambridge University Press.
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