Difference between revisions of "Template:Switch-to-(9OH-)risperidone"

From Psychiatrienet
Jump to: navigation, search
 
(8 intermediate revisions by the same user not shown)
Line 1: Line 1:
There are 2 switch possibities:
+
''There are 2 switch possibities'':
  
'''Number 1 (the general approach)'''  
+
'''Number 1 (the general approach):'''  
* Day 1: Switch to oral risperidone (or oral paliperidone): see this switch in the main cross table.
+
* '''Day 1:''' Switch to oral risperidone (or oral paliperidone): see this switch in the main cross table.
* Day 1-29: Maintain on oral risperidone (or oral paliperidone) and examine the effects.
+
* '''Day 1-29:''' Maintain on oral risperidone (or oral paliperidone) and examine the effects.
* Day 30: stop oral risperidone (or oral paliperidone) and administer paliperidone-LA: see this switch in the main cross table.
+
* '''Day 30:''' stop oral risperidone (or oral paliperidone) and administer paliperidone-LA: see this switch in the main cross table.
  
'''Number 2 (if a patient in the past reacted well on risperidon or paliperidone(=9-OH-risperidone))'''
+
Oral risperidone has better and more stable bioavailability properties than has oral 9-OH-risperidone=paliperidone. Food increases the absorption with 50-60% of the latter.
 +
 
 +
 
 +
'''Number 2 (if a patient in the past reacted well on risperidon or paliperidone=9-OH-risperidone):'''

Latest revision as of 15:57, 16 May 2011

There are 2 switch possibities:

Number 1 (the general approach):

  • Day 1: Switch to oral risperidone (or oral paliperidone): see this switch in the main cross table.
  • Day 1-29: Maintain on oral risperidone (or oral paliperidone) and examine the effects.
  • Day 30: stop oral risperidone (or oral paliperidone) and administer paliperidone-LA: see this switch in the main cross table.

Oral risperidone has better and more stable bioavailability properties than has oral 9-OH-risperidone=paliperidone. Food increases the absorption with 50-60% of the latter.


Number 2 (if a patient in the past reacted well on risperidon or paliperidone=9-OH-risperidone):