Difference between revisions of "Stop-clomipramine"
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{{Drugswitch | {{Drugswitch | ||
| from = clomipramine | | from = clomipramine | ||
− | | stop = {{StopAlgemeen}} | + | | stop = {{StopAlgemeen}}<ref>{{Pubmed|8889907|Coupland NJ et al. Serotonin reuptake inhibitor withdrawal. J Clin Psychopharmacol. 1996 Oct;16(5):356-62}}</ref>{{refBazire}} |
{{ReduceMedication|clomipramine|150|75|50|25|10}} | {{ReduceMedication|clomipramine|150|75|50|25|10}} | ||
}} | }} |
Latest revision as of 08:51, 19 July 2011
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- In general after long-term maintenance treatment, the best is to reduce the dose by about 25% every 4-6 weeks. An apt pharmaceutical dose (tablet, capsule, mixture) is not always available. In these cases one should be creative with dosing.[1][2]
- Another, more risky, possibility is being at a certain dose to use the following scheme:[3][4]
- 150 mg/day:
- Day 1: reduce dosage of clomipramine to 75 mg/day.
- Day 8: reduce dosage of clomipramine to 50 mg/day.
- Day 15: reduce dosage of clomipramine to 25 mg/day.
- Day 22: reduce dosage of clomipramine to 10 mg/day.
- Day 29 stop the administration of clomipramine.
- ↑ The UK Drug and Therapeutics Bulletin; 1999;37:49-52
- ↑ Editor: please note that not all dosages are available in pharmacy. So now and then you should be creative.
- ↑ Coupland NJ et al. Serotonin reuptake inhibitor withdrawal. J Clin Psychopharmacol. 1996 Oct;16(5):356-62
- ↑ Bazire S, Psychotropic Drug Directory 2010. Aberdeen: HealthComm UK Ltd; 2010.
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