Difference between revisions of "Amitriptyline-clomipramine"
From Psychiatrienet
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| − | {{ | + | {{Drugswitch |
| − | | | + | | from = amitriptyline |
| − | | | + | | to = clomipramine |
| − | | | + | | stop = |
* Gradually reduce dosage of amitriptyline to a maximum of 50-100 mg/day. | * Gradually reduce dosage of amitriptyline to a maximum of 50-100 mg/day. | ||
* When a dosage of 50 mg/day is reached, stop administration. | * When a dosage of 50 mg/day is reached, stop administration. | ||
| − | | | + | | start = |
* No wash-out period is needed. | * No wash-out period is needed. | ||
* Start administration of clomipramine the next day in a normal dosage of 50-75 mg/day. | * Start administration of clomipramine the next day in a normal dosage of 50-75 mg/day. | ||
}} | }} | ||
Revision as of 12:31, 4 May 2009
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Switch medication from amitriptyline to clomipramine.[1] [2]
Stop amitriptyline - Gradually reduce dosage of amitriptyline to a maximum of 50-100 mg/day.
- When a dosage of 50 mg/day is reached, stop administration.
Start clomipramine- No wash-out period is needed.
- Start administration of clomipramine the next day in a normal dosage of 50-75 mg/day.
- ↑ Switches are based on literature references on this page and expert opinions of the authors. The authors have used pharmacokinetic and receptor affinity properties to determine the switch schedules
- ↑ Stahl, S. M. (2013). Stahl's essential psychopharmacology: Neuroscientific basis and practical applications (4th ed.). Cambridge University Press.
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