Difference between revisions of "Vortioxetine-agomelatine"
From Psychiatrienet
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| − | + | {{Drugswitch | |
| + | | from = Vortioxetine | ||
| + | | to = agomelatine | ||
| + | | stop = | ||
| + | {{downVenla}} | ||
| + | | start = | ||
| + | * '''Day 7:''' simultaneously start administration of agomelatine in a dosage of 25 mg/day. | ||
| + | * '''Day 15:''' continue administration of agomelatine. If necessary, increase dosage of agomelatine to 50 mg/day.<ref name="agoswitch"> {{Pubmed|20196187|McAllister-Williams RH et al. The use of antidepressants in clinical practice: focus on agomelatine. Hum Psychopharmacol. 2010 Mar 1;25(2):95-102}}</ref> | ||
| + | }} | ||
Revision as of 15:56, 18 February 2015
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Switch medication from Vortioxetine to agomelatine.[1] [2]
Stop Vortioxetine - Day 1-14: gradually reduce dosage of venlafaxine to a maximum of 37,5 mg or 75 mg (slow release)/ day.
- Day 15: stop administration of venlafaxine
Start agomelatine- Day 7: simultaneously start administration of agomelatine in a dosage of 25 mg/day.
- Day 15: continue administration of agomelatine. If necessary, increase dosage of agomelatine to 50 mg/day.[3]
- ↑ Switches are based on literature references on this page and expert opinions of the authors. The authors have used pharmacokinetic and receptor affinity properties to determine the switch schedules
- ↑ Stahl, S. M. (2013). Stahl's essential psychopharmacology: Neuroscientific basis and practical applications (4th ed.). Cambridge University Press.
- ↑ McAllister-Williams RH et al. The use of antidepressants in clinical practice: focus on agomelatine. Hum Psychopharmacol. 2010 Mar 1;25(2):95-102
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