Difference between revisions of "Vortioxetine-clomipramine"
From Psychiatrienet
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{{Drugswitch | {{Drugswitch | ||
| from = vortioxetine | | from = vortioxetine | ||
| − | | to = | + | | to = clomipramine |
| stop = | | stop = | ||
* '''Day 1:''' reduce dosage of vortioxetine to 5 mg/day. | * '''Day 1:''' reduce dosage of vortioxetine to 5 mg/day. | ||
Revision as of 14:10, 3 March 2015
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Switch medication from vortioxetine to clomipramine.[1] [2]
Stop vortioxetine - Day 1: reduce dosage of vortioxetine to 5 mg/day.
- Day 7: stop administration of vortioxetine.
Start clomipramine- No wash-out period is needed.
- Dag 8: Start citalopram in normal dosage of 20 mg/day.
More information- Occurrence of the serotonin syndrome is not likely, but theoretically possible, so caution is necessary.
- ↑ Switches are based on literature references on this page and expert opinions of the authors. The authors have used pharmacokinetic and receptor affinity properties to determine the switch schedules
- ↑ Stahl, S. M. (2013). Stahl's essential psychopharmacology: Neuroscientific basis and practical applications (4th ed.). Cambridge University Press.
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