Difference between revisions of "Citalopram-vortioxetine"
From Psychiatrienet
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| − | [[ | + | {{Drugswitch |
| + | | from = citalopram | ||
| + | | to = vortioxetine | ||
| + | | stop = {{StopCitalopramAtDose}} | ||
| + | | start = | ||
| + | * A wash-out period is not necessary. | ||
| + | * Start administration of vortioxetine the next day in a dosage of 10 mg/day. | ||
| + | | info = | ||
| + | * {{theorSS}}<ref>[[European Medicines Agency]] | SmPC Brintellix 5 mg. </ref> | ||
| + | }} | ||
Revision as of 13:39, 4 March 2015
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Switch medication from citalopram to vortioxetine.[1] [2]
Stop citalopram - Gradually reduce dosage of citalopram to a maximum of 20 mg/day, when this dosage is > 20 mg/day.
- When a dosage of 20 mg/day is reached, stop administration.
Start vortioxetine- A wash-out period is not necessary.
- Start administration of vortioxetine the next day in a dosage of 10 mg/day.
More information- Occurrence of the serotonin syndrome is not likely, but theoretically possible, so caution is necessary.[3]
- ↑ Switches are based on literature references on this page and expert opinions of the authors. The authors have used pharmacokinetic and receptor affinity properties to determine the switch schedules
- ↑ Stahl, S. M. (2013). Stahl's essential psychopharmacology: Neuroscientific basis and practical applications (4th ed.). Cambridge University Press.
- ↑ European Medicines Agency | SmPC Brintellix 5 mg.
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