Difference between revisions of "Aripiprazole LA-Flupenthixol LA"

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Revision as of 12:04, 17 March 2015

Aripiprazole
long acting
Type Antipsychotic
Group Atypical AP
Other use moodstabilizer
links
Medscape Aripiprazole
EMEA abilify
PubChem 60975
PubMed Aripiprazole
Kompas (Dutch) Aripiprazole
Wikipedia Aripiprazole
Fluphenazine
long acting
Type Antipsychotic
Group Phenothiazines
links
Medscape Fluphenazine
PubChem 3372
PubMed Fluphenazine
Kompas (Dutch) Fluphenazine
Wikipedia Fluphenazine

Switch medication from Aripiprazole LA to Fluphenazine LA.[1] [2]

Nietinrijdenbord.png Stop Aripiprazole LA
  • Day 1: Last depot injection
Eenrichtingbord.png Start Fluphenazine LA
  • Start depot according to general dosing advice on the day you normally would have injected the former depot.
  • Testing for acceptance and possible allergic reactions in a low dose can be carried out earlier.
Infobord.png More information
  • During this switch you could monitor ECG, especially in patients prone to QT-conduction problems.
  • There is a possibility of QT interval prolongation.[3]
  • More information you'll find in the summary of product characteristics (SPC) of aripiprazole depot injection. [4]
    StopDepotStartArip.jpg
Nietinrijdenbord.png — Aripiprazole LA
Eenrichtingbord.png — Fluphenazine LA


  1. Switches are based on literature references on this page and expert opinions of the authors. The authors have used pharmacokinetic and receptor affinity properties to determine the switch schedules
  2. Stahl, S. M. (2013). Stahl's essential psychopharmacology: Neuroscientific basis and practical applications (4th ed.). Cambridge University Press.
  3. Stöllberger C, Huber JO, Finsterer J, Antipsychotic drugs and QT prolongation. Int Clin Psychopharmacol. 2005 Sep;20(5):243-51.
  4. http://www.ema.europa.eu/docs/en_GB/document_library/EPAR_-_Product_Information/human/002755/WC500156111.pdf SPC of the European Medicines Agency on aripiprazole depot
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