Difference between revisions of "Hypericum-maprotiline"
From Psychiatrienet
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* If necessary, increase dosage of maprotiline to 50 mg/day. | * If necessary, increase dosage of maprotiline to 50 mg/day. | ||
| − | * Start low, go slow.}} | + | * Start low, go slow. |
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Latest revision as of 10:28, 14 October 2015
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Switch medication from hypericum to maprotiline.[1] [2]
Stop hypericum - Administration of hypericum can be stopped abruptly.
Start maprotiline- Day 1-7: a wash-out period of one week is necessary.
- Day 8: start administration of maprotiline in a dosage of 25 mg/day.
- If necessary, increase dosage of maprotiline to 50 mg/day.
- Start low, go slow.
More information- Occurrence of the serotonin syndrome is possible without wash-out period.
- ↑ Switches are based on literature references on this page and expert opinions of the authors. The authors have used pharmacokinetic and receptor affinity properties to determine the switch schedules
- ↑ Stahl, S. M. (2013). Stahl's essential psychopharmacology: Neuroscientific basis and practical applications (4th ed.). Cambridge University Press.
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