| to = bupropion
| stop =
* Gradually reduce dosage of fluoxetine to a maximum of 20 mg/ day, when this dosage is > 20 mg/day. * When a dosage of 20 mg/day is reached, stop administration.{{stopFluoxetine1}}
| start =
* '''Day 19-2837:''' administration of bupropion in a low dosage of 150 mg/day.* '''Day 29 37 and on:''' if necessary increase bupropion to 300 mg/day.
| info =
* Bupropion inhibits CYP2D6 which metabolizes fluoxetine.
* Because of the normal half-life of 1 week of desmethylfluoxetine, there should be a low dosing of bupropion during 4 weeks.
{{review}}
}}